Tips for the Newly Floxed

Fluoroquinolone Toxicity First Steps

Some tips for those who are dealing with the horrible effects of Cipro/ciprofloxacin, Levaquin/levofloxacin, Avelox/moxifloxacin, Floxin/ofloxacin, or any other fluoroquinolone antibiotic, can be found in the post, “I’m Floxed. Now What?

Excerpted from the post:

First, read through the recovery stories on Every healing story is different. The journey through fluoroquinolone toxicity has not been the same for any two people. Even though each story is different, each story has some valuable wisdom and guidance in it. As you’re reading through the stories, I suggest that you write down the healing tips and steps that resonate with you. Try those things one-by-one and see if they work as well for you as they do for the person who recovered from fluoroquinolone toxicity and wrote the story.

Second, the ebook, The Fluoroquinolone Toxicity Solution*, has helped many people through fluoroquinolone toxicity, including Ruth, Cindy and Daniel. It gives particularly good guidance for those looking for supplements to help them to heal from fluoroquinolone toxicity.

You can find support, guidance and advice through many web sites and social-media groups. Comments on the home page of are typically responded to quickly and there is a wealth of information in the past comments. The Fluoroquinolone Toxicity Group on Facebook is also an excellent resource for support and information that also has years of helpful posts stored on it. (Try not to get overwhelmed by these sites, and if you do get overwhelmed by them, I recommend that you step away from them until you are emotionally able to handle being on them.)


Please feel free to add additional tips in the comments section below. Thank you!

75 thoughts on “Tips for the Newly Floxed

  1. Aidan Walsh April 18, 2016 at 6:47 am Reply

    Where can someone get the DNA Adduct test done in UK & other blood tests the Toxicologist mentioned in his pdf JKing? Which test is it that shows the DNA attached as well? thank u appreciated lots…

  2. Shelly September 6, 2016 at 9:57 am Reply

    Thank you. Are there any medical tests that have been found that can help measure the body’s response? For example, do most people affected by cipro or drugs like it show bloodwork abnormalities?

  3. joanne September 9, 2016 at 3:38 pm Reply

    fluorine attacks the magnesium in your body (attaches to it and pulls it out from where it is, mostly in tendons, cartilage, etc.). so low magnesium is often the reason for injury–try to take it asap. a blood test will not show low magnesium generally, as most of the magnesium in your body is not in your blood (i think 1% or so is in your blood). the rest is elsewhere, and with the fluorine pulling it out of your body, the structures suffer. Athletes and people under stress tend to have low magnesium levels, which is why “participation in a sport” is
    a risk factor (Mayo clinic article, 2011, by Hall, Finnoff, Smith).

    in my case, i showed nothing in bloodwork at all, but my Achilles’ tendons were badly damaged, overnight, as were other things. they are getting better, but not healed yet, being overseen by a cautious physical therapist willing to learn about fq’s has been helpful.

    If you are taking a fluoroquinolone still and have to (i.e. you have plague) there is some thing (NAC?) that doesn’t interfere with its antibiotic action. Magnesium interferes with its action.
    If you are told there is no drug besides a fluoroquinolone that will work, that’s just not true, unless you can’t take sulfa drugs or doxycycline etc.

    good luck!

    • Claire Jones January 2, 2017 at 1:35 pm Reply

       I just came across this. I apologise if it is already on floxiehope.

      Information for Newbie’s
      This section contains information for people who are new to Adverse Drug Reactions from fluoroquinolone antibiotic therapy. We will update this section as we gather information.

      This information comes from an ADR victim who has conducted extensive independent research after being floxed on numerous occasions.   
      One of the quinolone-induced adverse reactions most difficult to tackle is neuropathy. Every floxie has a degree of neuropathy, varying from mild to extremely severe, depending on the level of intoxication. I currently belong to the latter group, but as I have been floxed several times, I also know what it is like to belong to the mildly intoxicated group. 
      Apparently there are at least two main detrimental mechanisms that quinolones provoke on the nervous system.
       First comes a chemical assault. According to some medical specialists, it binds to the GABA receptors, thus altering the normal neurological patterns. The nerves also become hypersensitive to many substances to which we were accustomed before, like caffeine for instance. According to those doctors, the toxicity acts mainly against the central nervous system, causing insomnia, restlessness, panic attacks, weird dreams and thoughts, suicidal tendencies, seizures or preseizure states, difficulty concentrating, loss of short and long term memory, and many more.  
      But on top of the chemical intoxication there is an even stronger pathway towards severe damage. If the nervous system was just affected chemically and became permanently on edge, any soothing, calming substance would be of help. That is not the case, and most products, drugs or supplements that in a normal situation help to relax and ease the over stimulation symptoms, do exacerbate them. For example, if you take lecithin supplements, or serotonin inducers, your symptoms will surely worsen a lot.
       Because as strong as the chemical insult is, there is another, even stronger alteration of the whole body’s system. The quinolones cause a small vessel vasculitis, a narrowing of the clear inner duct of the smallest arteries and veins that supply oxygen, nutrients and remove the byproducts of their metabolic activity. The vasculitis is massive and arise immediately (in allergic reactions) or has a progressive onset that becomes apparent only long afterwards when the organs and tissues are symptomatic after a progressive ischemic (blood flow deprivation) process. 
      The vasculitis could be an inmuno mediated deposition of immunological complexes in the walls of the vessels, which in turn would explain that symptoms are pretty much the same for some people that have taken just one pill and for those that have taken more than 200.
       The only way of proving it is through a muscle biopsy. Such a biopsy is tremendously difficult to perform adequately. Firstly you have to select the more affected muscle, what causes further inconveniences, and then find a laboratory that knows perfectly well how to preserve the sample, prepare the slices, reactives and what to look for in a case like this. It is possible but not within the reach of a standard laboratory. 
      Some parts of the body become damaged in the first place, such as some tendons and connective tissues, that are very little irrigated areas. Others like cartilages simply die off (the chondrocites of the four layers). And many other parts start a necrotizing or dysfunctioning mechanism and some weeks or months later the symptoms appear with full force:  
      -joint pains, mostly neurological, that on average appear at the 3 month mark
      -hearing problems, tinnitus, head pressures, jaw problems, and many many more
      -vision problems: floaters, photophobia, trailing, wandering lights, loss of vision, diplopia, focusing problems, blurred vision, and many more.
      -dry eye, dry sinus, sometimes dry mouth, that tend to be permanent, mimicking a Sjögren’s syndrome.
      -very cold hands and feet; poor circulation, soft erections or semi impotence in men
      -extreme negative reactions and relapses due to stressing situations
      -electrical (neurological) alterations of heart rhythm (palpitations, arrhythmias) that have ended with some fellow floxies wearing a pacemaker
      -extremely persistent and long lasting neuropathies all over the body, some of them very similar to diabetic neuropathies.
      We all have been tested negative to all the markers, titers, and so on. Most of the EMGs provide negative results, but not all. When there are only pains, fasciculations, tremors, twitchings, the EMG’S are negative. If there is also strong numbness then they can be positive. The main mechanism and the most difficult to cure is vasculitic. It is the origin of nearly all of our neurological problems. 
      Our neuropathies are systemic (body) and peripheral. The systemic ones are more asymptomatic, so it is difficult to make a follow up of them but they have enough manifestations to be recognized like intestine spasms (some extremely painful that have made some members to black out), bladder dysfunctions, heart arrhythmias, and the above mentioned central nervous system disorders. 
      The peripheral neuropathies can be permanent in severe cases. They manifest like pains in hips, knees, ankles, shoulders, wrists, tingling, twitchings, throbbing pains (very characteristic), numbness, fasciculations, etc. 
      The peripheral neuropathies of the floxies are a common cause of atrophy of muscles, specially quads, peroneal groups, calves, biceps, triceps and hamstrings. The wasted muscles do not support the joints properly, and thus the joint pains increase and lead to overloads in cartilages and other structures, perpetuating the cycle of pain-limitations-more atrophy-more pain-destruction. 
      Floxies tolerate badly any strenuous exercise. The demand of oxygen in the muscles cannot be matched by the vascular system, and then muscle breakdown leads to great pains some hours after exercise, with increased CPK levels in serum tests for at least one to three days. On the other hand, moderate exercise promotes circulation, improving symptoms slightly. 
      Peripheric neurological pains at night can be sometimes excruciating, specially after exercise. Adding this to the general insomnia and brain for state, makes life miserable. In other words, this condition is very debilitating. Some fellow members of the FQ group could not bear it any longer and took their lives. 
      Drug induced vasculitis are frequently recorded in the medical literature. It is common knowledge that they can start months or even years after the discontinuation of the drug. There is no cure protocol, neither any suggestion in order to counteract their negative effects. 
      The only really helpful recommendations are the following:
      avoid any further contact with these drugs
      avoid vasoconstrictors
      promote vasodilators
      avoid any mega doses of vitamins
      take some magnesium, calcium
      depending on the peripheral neuropathies, take some vitamins of the B group, perhaps benfotiamine to
      avoid long term treatments with corticoids.  I am not so sure that short treatments should be avoided too
      avoid anti-inflammatory (make symptoms worse, that is for sure)
      Our needs are to find a scientific research group or a doctor that cares enough and has the determination and funding to conduct a program with some volunteers that may render useful results like:
      -way of damage
      -a diagnostic method to asses severity of damage
      -some suggestions towards speeding recovery
      -patterns of conduct for floxies
      -recommendations to severely cut down applications of these defective drugs.
      Unfortunately, when all these questions are answered, quinolones will be probably out of the market as first line antibiotics, but it will be too late for many of us.

      • Susan Richards September 1, 2017 at 5:31 am Reply

        Hi Clare – Can you give me the link to the source for your information on QUINOLONE INDURED NEUROPATHY? I’d like to give this to my doctor who is treating me for anxiety, panic, & insomnia. But he’ll ask for the source. Thanks.

      • Anna October 5, 2018 at 5:54 pm Reply

        Hi Claire,
        I’ve recovered from all symptoms, but I was hit worst by an eye reaction. I took one pill and had tightness behind the eyes, extreme light sensitivity/blurred vision which led to an ER visit. Thankfully my vision came back and pain left, but now the muscle under the eye is still swollen, looks like an eye bag, but it isn’t.
        Also, weird sensations in sinus area, but never had sinus issues of any kind prior. Ophthalmologist confirmed the eye itself is healthy, and the bulge is not the fat pad, but inflammation of the muscle or orbital area. I am afraid to take steroids for the inflammation and I wonder if it is an immune response to the medication.
        Any tips for getting rid of the swelling? Any guess why swelling persists after other symptoms went away?

        • SAM October 10, 2020 at 11:31 am

          Newly affected. 10/04/2020. Currently severe swelling in throat, neck, TMJ, eyes & mouth dry, have clicking, poping, tightness & spasms in back, major joints & major tendons. Tendon pain starting today. Head pain & headaches with light sensitivity & spots.

          I found warm to hot wet compresses help aleviate some issues & hard swelling (lump) & general swelling used over time better than ice does.

          I would consider holding epsom salt soaked facecloth on area but watch not get it in eye. It will take a while to reduce site (hard) swelling. My elbow joint (megadose floxied by IV in hospital 10/04, hard lump is at injection site) has hard swelling lump which lump has been reduced by half over 3 days with compress. I am on magnesium now. Took epsom salt bath thisorning. Hoping & praying to beat this quick. Thank you so all much for these posts! God Bless You All 🙂

      • Mike June 13, 2019 at 7:37 am Reply

        What is considered “severe” by peripheral neuropathy standards? If you can walk miles a day and work through mild discomfort, is that mild?

        I was told that peripheral neuropathy from any medication-induced toxicity typically subsides completely over time, depending on how much was taken. Chronic illnesses such as diabetes, etc. are conditions that perpetuate the possibility of permanent neuropathy.

        • Erik January 13, 2020 at 11:16 am

          Hey Mike, I originally tool levaquin in 2006 and recovered from horror in 2013. Few days back I took claritromicin/amoxicilin for h pylori. After only 2 doses all symptoms or neuropathy returned back , anxiety I couldn’t believe that damage from levaquin was still there and now awoken by this. You said that more neuropathy recoveres and I am so holding to that hope. It is scary that I experienced same symptoms 14 years after and while I recovered.

  4. cindy Jones December 1, 2016 at 2:24 pm Reply

    how much magnesium does one have to take and for how long.

  5. Shaun February 7, 2017 at 7:43 pm Reply

    Wow, it’s been a month since I was floxied (Cipro), and I’m trying to get on the Facebook Fluoroquinolone Toxicity group. Would you know how long the requests take to get granted?

    I’m in Singapore and there seems to be very little support available here. Everything is controlled by the Health Sciences Authority which does not recognize fluoroquinolone toxicity.

    It started with my swollen feet and calves and now my shoulders and back, knees and joints hurt. I can’t even hold my mobile phone for too long as that hurts too. All the symptoms low vitamin d, iron, magnesium. Abdominal pain and diarrhea.

    Anyone from Singapore who had been floxied too?

    • Lisa February 7, 2017 at 9:40 pm Reply

      Hi Shaun,

      The admins of the Fluoroquinolone Toxicity Group send an email to people to make sure that they are aware of the rules of the group. Check your Message Requests folder on facebook to see if they’ve reached out to you.

      There are some “floxies” in Singapore who have participated in commenting on this site, and in the Fluoroquinolone Toxicity Group in the past. Most of the activity is in the US, but there are people who have been hurt by these drugs all over the world.

      I hope that you are able to get the support you need either online or in person!

      Best regards,

      • Wendy June 29, 2018 at 8:01 pm Reply

        Do not get on that site . Bunch of negative people who will tell you that you’ll never heal.when asked what their health habits are they claim they’re heroin or drug users. Everyone on there are the same trolls . I’ve spoken to 50 that have recovered and are NOT on the site. You’ll heal but it will take time and patience. Also don’t read the floxie hope stories. People claim they healed on x time then when directly asked that time is doubled or tripled. A useless site/ stories. Just do your own thing. You’ll be ok.

        • Tammy Lynn Fayette November 6, 2019 at 4:03 pm

          What sight do you use then of people that have recovered?

  6. Natalie Krul April 18, 2017 at 4:00 am Reply

    Hello, can you provide any antibiotic alternatives that are considered safer and non-fluoroquinolones? I have a health situation that will require antibiotic and want to make sure my doctor prescribes me something safe…..

    • Lisa April 18, 2017 at 8:32 am Reply

      Hi Natalie,

      Most people seem to be okay with penicillin, tetracycline, and cephalosporins.


      • Brenda November 27, 2017 at 8:17 am Reply

        Thank you for this post! ❤ I took Macrobid after being floxed and it made my Cipro side effects reappear. 😡

        • erik January 13, 2020 at 11:22 am

          Hi Brenda,
          Me too I took claritromicin 14 years after levaquin (on12/19) and only 2 doses. All symptoms which ones dissipated all returned; I could not believe !!!. IS this forever? Did your symptoms subsided after some time?

        • Tricia February 1, 2020 at 6:21 am

          I know this is an old post, but did u recover from Bactrim side effects?

        • Tricia February 1, 2020 at 6:24 am

          Brenda, please disregard my post from below. I meant did you recover from macrobid side effects….not bactrim

      • Ashton August 9, 2020 at 9:42 am Reply

        Have you heard of any issues with vaginal corticosteroids or clindamyician?

        Thank you.

        • Ashton August 9, 2020 at 9:43 am

          And is diflucan safe for women to take post floxing?

    • Susan June 13, 2018 at 6:55 pm Reply

      Some people use oregano oil for infections.

  7. Penny Franklin April 21, 2017 at 3:13 pm Reply

    Lisa, is it typical for the teeth/ears to hurt. I’m not even sure it’s my teeth. The pain moves from side to side and top to bottom.

  8. Faisal May 18, 2017 at 5:38 am Reply

    Hello all,

    It’s ok if I take calcium and mag and d for 16 months every day with vitamins C 1000 ?

  9. Singh July 22, 2017 at 9:59 am Reply


    Has anybody taken local anesthesia after being floxed? Its my 5th week after being floxed and I can’t even walk without crutches. Even with crutches, I can only take a few steps but I have to first ice and put tighter strechbands around my heel and tendon because as I stand, I feel like I am standing on thousands of needles and don’t feel firmness in my heel. If I don’t put tight bandages, it feels like my heel is just going to burst (I haven’t even dared to try it though but even with bandages it feels this way).
    However, I have a cystoscopy (male) scheduled after a week and the doctor is going to push local anesthesia into the gentleman’s part before he can put scope it and take a look at bladder. Would anyone please share their experience, any article, knowledge or anything before I go for it. I am scared but like many have written, doctors have no clue of anything and their thought is ‘local anesthesia’ is not gonna do anything as it is going to wear off….And I am wondering if I should postpone it, cancel it etc etc etc. ANY information would be greatly helpful. I hope people are still reading this page.

    • Ernesto February 4, 2019 at 6:01 pm Reply

      Hi. Did you ever follow through with the procedure? How did you feel after the anastesia?

  10. J Robinson October 23, 2017 at 1:18 pm Reply

    Has anyone seen any studies that relate fluoroquinolone antibiotic toxicity to people who live in areas that have high natural levels of Fluoride in the water? I grew up in a area (Mojave Desert, California) with naturally high levels of fluoride in the water.

  11. dp9113 October 24, 2017 at 3:45 pm Reply

    I am just my 3rd week in and need hope. My bp is skyrocketing my headaches are unbelievable. Pain and anxious all the time. I am taking magnesium and
    Coq10. Someone anyone help me please. I am on bystolic 10 mg and my bp is shooting up to 200/120 after I relax for 30 minutes its goes to 145/89 this is insane. I have a Dr appointment on Thursday 2 days from now. God help me this is awful. I’m hurting everywhere. I took cipro for 10 days for sinusitis.

    • Brenda November 27, 2017 at 8:11 am Reply

      Sorry to hear that, I am recently floxed also. I have found that liquid magnesium chloride helps me. And detox baths or feet soaks with epsom salt and baking soda. I also use hymalayan salt sometimes. Pray you feel better.

    • Brenda December 18, 2017 at 1:38 pm Reply

      I was wondering how you are doing. I pray much better! Take care!

  12. Brenda November 17, 2017 at 4:13 am Reply

    I am 17 days floxed. Took a total of 3 pills on 11/1 & 11/2. I started with leg pain and took myself off. Now it seems the effects of cipro are morphing into other things. I have been doing epsom salt baths to detox and have started on liquid magnesium. I am also going to start taking coconut oil. Anything else I can be doing that has helped others? Thank you for your encouragment through the account of your experience. May the Lord bless you!

  13. Brenda November 27, 2017 at 8:06 am Reply

    I am floxed since Oct. 2nd this year. My side effects seem to be getting better but I took an antibiotic (Macrobid) a day an a half and some of my side effects returned. Is there a natural herbal supplement that anyone has had success in getting rid of an UTI? Thanks- Brenda

    • Janeth December 17, 2017 at 8:02 am Reply

      Brenda I hope you get better soon, macrobic is like ciprofloxacin, take azo with precaution , it will make you pee yellow and drink a lot of water, flaxseed water (antiinflamatorio), parley tea(it make you pee a lot), I will comment my case, I got pregnant and at 37 weeks I got úti because I make love with my husband but I think it was just and irritation, the doctor toll me I had uti, I never have uti in my life also the test came back negative, but they prescribed me macrobic telling me it is safe for pregnant woman and my nightmare start there, I just took one , thanks god I don’t like to take medication , by that day my leg start to hurt and I start to have tendinitis , my baby born at 38 weeks but I was feeling that I was having uti since the day that I took macrobic, so the Doctor again prescribed macrobic for me is the same as Cipro, it give me the same issues, the most horrible including memory loss, them the doctor prescribed Cipro , thank god I got to floxi hope page and somebody says that he got blader inflammation after taking Cipro , it feels like he was having uti, and he took flaxseed water …….. I am glad that I read his message because after that I start to take flaxseed water ( boil flaxseed , drink just water) all day and in a week my horrible stomach and blader pain when away and I could pee, I was worried because all the test for uti was negative, macrobic, Cipro produce ibs and blader damage too , my tummy looked like I was 3 months pregnant because the pain and inflammation from macrobic and Cipro, after the flaxseed water it look normal but now I have to still take because when I eat something wrong I got tummy ache…. I think we have to take care our tummy for life, good luck

      • Brenda December 18, 2017 at 1:35 pm Reply

        Thank you for your response and help. I will try the flaxseed water. Praying you are doing better! And that your baby is fine as well.

    • Don Mowers March 6, 2018 at 8:32 am Reply

      I don’t see anyone suggesting D-Mannose as a help and in many cases a preventive for urinary tract infections. Most Urologists will suggest that you drink cranberry juice. Why? Cranberry juice contains D-Mannose. I wonder just how many of those doctors even know why they are suggesting cranberry juice. D-Mannose works because it makes the urinary tract slippery and inhibits the bacteria’s ability to stick to the walls of the bladder and the rest or the urinary tract. Quote from a user. “This product is a natural sugar (found in cranberry juice as well as in other fruits and plants) that is godsend to women”. Another quote. Technically, D-Mannose is a “simple sugar.” Functionally, it nourishes the healthy flora that colonize the membranes of the urinary tract and keep us in balance. Pure D-Mannose is available in both pills and powder. Research it. Get it. Use it.

  14. Janeth December 17, 2017 at 7:44 am Reply

    Hi , I was floxed April 2016, then June and October 2016, i had all the horrible simtomas , I loss my memory, mental flog, neuropathy pain, tendinitis arthritis reumatismo ibs gastritis, blader problems , liver, kidney destroy, ear pain, etc, I was getting better, by August , September, november , ( I took to get better flaxseed water, multivitamin, complet aminoacid , probiotic, wheat grass, milk thistle ), but by December when the cold start my tendinitis came back and my bone pain , and my mental fog, so reading some advises from glories , I add caltrate 600+d3, I go back to be pain free after a week but I still have to use 3 pants 😀, I am 32 , and now I loss my confidence in the doctors, I was really healthy, never smoked or drink, I eat healthy food, I don’t like the doctors now.

    • Brenda December 18, 2017 at 1:37 pm Reply

      So glad to hear you are doing better! I will certainly try the flaxseed water. I am doing detox water now. Thank you!

  15. Shanks December 19, 2017 at 8:22 am Reply

    Hi – I believe i am floxed as well as of last Tuesday. Last week, i was prescribed Cipro for a infection that did not warrant this poison. I took the dosage for 4 days when i ran into this site while doing research on that antibiotic. I should have done it before i took the first pill as i always do and would have avoided all this anxiety.Anyways now that damage is done, i am looking for some starters. I did purchase the guide along with bonus documents. Have started on Mag, MultiV, Probiotics for last 2 days. I have not seen any swelling as of now. Most of the symptoms appear while sleeping. Is that something normal?

    My symptoms:
    1) Muscle twitching all over body for few minutes ( in the middle of night that woke me)
    2) Leg stiffness below hip ( mostly in night), along with numbness sometime,.
    3) stress ofcourse.

    I have always eaten Organic food and this is my first stint with Antibiotic which is not going well.

    Any other inputs pleases?

    • Janeth January 16, 2018 at 5:27 am Reply

      Take amino acid complete, this help me too

  16. Alban December 22, 2017 at 8:14 am Reply

    First of all, I am sorry for my poor language, I am french and discovered your websites a few hours ago.

    A friend of mine experience a fluoriquinone toxicity syndrom.
    Since I am a PhD biologist working for both pharma and cosmetic industry, she came to me for advice.

    I read a few papers on the toxicity itself and her particular case match perfectly. But these papers fall short when it comes to “what to do after toxicity”.

    In particular, she observed a positive correlation between meat intake and joint pains.
    We confirmed that farm massively use these antibiotics even when the beast is healthy. Organic farms are allowed to use antibiotics aswell.
    Unfortunatly, I didn’t find anything on pubmed nor google scholar about meat intake on people suffering of fluoroquinone syndrome.
    Does anyone have references about it?
    Is it well-known in this community that meat induce join pain?
    Does anyone consider to test it’s own meat with test kit (eg : ?
    Do we know the toxicity dose of fluoroquinone on people suffering from intolerence?

    Thank you very

    • Lisa December 22, 2017 at 2:20 pm Reply

      Hi Alban,

      Thank you very much for doing research on behalf of your friend! That is very kind and generous of you.

      Several people have reported worsening symptoms after eating meat, and it is assumed that the meat is contaminated with fluoroquinolones. Here is Ben’s story in which he attributes his symptoms and relapse to consuming fluoroquinolone-contaminated meat – Antibiotics are used widely in agriculture, and it certainly makes sense that people are being hurt by fluoroquinolone residues in their meat. However, I have not seen any research articles that note that there are fluoroquinolone residues or traces in meat that is consumed by humans. So, most of our evidence of that is anecdotal.

      Many people suffering from fluoroquinolone toxicity syndrome experience food intolerances of various types. A couple theories around this are:

      1. Fluoroquinolones are potent antibiotics that kill both harmful and helpful bacteria in our guts. A healthy and balanced gut biome is necessary for a properly functioning GI tract, and fluoroquinolones disrupt gut biome balance, leading to food intolerances.
      2. Fluoroquinolones downgrade GABA, and fluoroquinolone toxicity is similar to benzodiazepine withdrawal. GI disturbances and food intolerances occur in those who are going through benzodiazepine withdrawal, and perhaps the downgrading of GABA that occurs with fluoroquinolones does similar things to people who are “floxed.” Here’s a post with several links that may be helpful –
      3. Fluoroquinolones may trigger histamine intolerance and mast cell activation. Here is a post, along with links, exploring that possibility –

      There are journal articles that relate to each of these theories. I don’t think anyone has any really solid answers though–mainly because fluoroquinolone toxicity is rarely recognized as a syndrome.

      I hope that you are able to help your friend. Thank you again for looking into this.


  17. DaveNJ January 12, 2018 at 11:18 am Reply

    I have been floxed now for about a month. I’ve read all of the material on this and other sites and conclude that no one really has an answer for those of us who have foolishly taken these drugs recommended by our doctors.

    This problem needs to be directed back at the pharma companies that are selling these drugs. What we need is a class action suit, not to collect money, but to force the drug companies to find an antidote to the suffering they have caused. I wonder if there are any lawyers on this thread that would be interested in leading this charge.

    • Lisa January 12, 2018 at 11:22 am Reply

      Hi Dave,

      Lawsuits and studies are sorely needed, for sure. I suggest that you reach out to a law firm that is suing Bayer or J&J for fluoroquinolone damages. There are some listed under the “Law Firms” heading on


    • toby September 10, 2018 at 9:01 am Reply

      I agree with this line of thinking, I called Johnson and Johnson, and the best they can say is they will do a literature search for me….. They have a fleet of Dr’s and scientists and cant make any recommendations

  18. DaveNJ January 12, 2018 at 11:53 am Reply

    Lisa, Thanks. I checked out the law firms. It appears that they are interested only in cases that involve peripheral neuropathy or damage to the aorta. We need a not-for-profit firm to champion the cause of those suffering with tendon damage, etc. Wonder if such a firm exists.

    • Christy January 13, 2018 at 9:13 am Reply

      I took 4 doses of Cipro for UTI from a walk in medical clinic (5 days ago). I am having horrible side effects and very scared. Shaking and muscle twitches and twitching, headache, weakness all over, difficulty to bend down to use restroom and walk down stairs, walking slower, and very nervous. Please help with anything to do or not to do. I’m so overwhelmed. Thank you.

  19. Dan Z February 15, 2018 at 7:58 am Reply

    Hello! I took fluoroquinolone for 2 weeks and started to have problems with tendonds immediatly after I stopped. I took a lot of suplemments and I don’t know which one worked. But now after 8 months I have no more significant effects.
    The biggest problem was with fasciitis plantar tendonds.
    The only thing I sure it worked was as an specific single identifiable solution was soundwave shock teraphy. I also suspect think ACC and magnesium helped a lot.

  20. Tina May 31, 2018 at 7:59 am Reply

    i took Cipro and Avelox for what the MD thought was Diviticulosis..My colon is now all messed up .Lost weight cant gain weight. Only eating starches and protein. Go everyday to bathroom with out eating any roughage which I used have to eat a lot ..Stools have changed texture , shape ..not to get graphic. I take a probiotic and now my Doc wants me to Xafaxin?? Which is another anitibiotic? I have abdominal pain to and my legs ache at night doc is blaming the Cipro and Avleox. ANy help will be appreciated ..anyone else with same symptoms? I took the antibiotic end of March this is May

  21. Anna July 19, 2018 at 4:49 pm Reply

    I took only ONE pill, and had tightness in the back of eyes/blurred vision (most likely tendons or muscle spasms) and popping joints. WTH!? Anyone here have only one pill and experience this? I already am on day 2 of 750mg Mag Citrate & 2000 IU Calcium, feeling a bit better today.

    • Brenda November 6, 2018 at 11:41 pm Reply

      I took 3 pills a year ago and still have some “side effects” that I deal with. How are you doing? My sight got worse after Cipro. I had tendon pulls and cramps, thought I would end up in a wheelchair. I am better now. But still deal with leg pain, some cramping, weakness on my left side, heart palpatations, memory loss, fatigue. How are you doing?

  22. Janeth August 1, 2018 at 6:00 pm Reply

    Hi , I hope everyone is getting better, and always looking for for something that can help us to get better, I am came back here to let you know that I found the cure for our mental fog and other brain issues, including ear pain, eye pain, I came across with protocol of Gregorio J Placeres on Facebook, he make a bunch of children recover from autism with MMS that you can get on eBay or one wedside were suposted is safe, this MMS oxides metals in our body and make them cane out, I just try a simple protocol which consist in having honey with cinnamon 3 hours before taking MMS with gatore the one that has sugar , in my case I am 100 I have to take 7 drops of MMS in 70 ml of gatore, I can’t eat 2 hour before having MMS AND after one our, preferable go to sleep and I promesa since the first time you will be better in your head, so far I took this protocol for about a month and I can say I am free of mental fog, ear pain, eye pain and sensitivity, also took care part of my horrible neuropathy pain , At the beginning I was scare to take the MMS Because I dint have more information but then I decided to try it, just google MMS OR go to Facebook and find Gregorio J Placeres. His protocol for autism is more complex, but watching his videos the most important is cinnamon, any real honey, MMS ($16 or $20 per bottle that will last for a year ), there is a safe place we’re you can get MMS , you can get MMS HERE or eBay, I will described for my weight how I did, I am 102 pounds so for my weight I have to take 7 drops of MMS, before you drink MMS YOU HAVE to prepare your stomach with honey and cinnamon ( Gregorio have measurements for this )but I just mix 20 spoons of cinamoon with 20 spoons with honey and I leave it seat for 2 hours , then you have to have one spoon each our but I just took the first time one spoon 1/2 hour before each meal, after the last spoon I wait 3 hours and I have the MMS 7 drops in 70 ml of gatore the one that has sugar, the reason you take cinnamon with honey is for 3 reason, 1 to protect your stomach,2 acidification of stomac, 3 here to kill Candida, ones the stomach is acidic( I don’t really feel acidic stomach), you take the mms with gatore after 3 or 4 hour of cinamoon or honey, ones the mms and Gatored get to the stomach it turns into Gas, that Gas is the one that will help you to take metals from your body through oxidation, after I saw good benefits in the week 2 I took twice , I always maked sure that I take cinamoon with honey 3 hours before the mms with gatored, why the gatore has to be with sugar , it is because the sugar will help to activate the MMS IN your tummy. Good luck I hope this can help, now I am with a sharp mind, I still have the other articulation problems and muscle but are less, I think this MMS help me too. 🌹I wish to everyone recovery soon

    • Janeth August 1, 2018 at 6:24 pm Reply

      Sorry my English is not good but I hope you got the idea , thanks 😀

    • Janeth August 1, 2018 at 6:50 pm Reply

      I forgot to mencione I got floxed on April 2016 and I had the worst side effects , I could walk, I had all the symptoms since my stomach pain until tendinitis …, etc, I did try active charcoal , bentonite c, carbon 60, height levels of vitamins, coconut oil, fish oil, etc to recover my mind but the only one that help me was the MMS, I got my memory back, I don’t have mental fog, I can read and retain information, I have to say mentally I am better that before being floxed😀

    • Janeth August 1, 2018 at 7:09 pm Reply

      I forgot to menciones MMS IS JUST ONE BOTLE, eBay sells 2 bottles but use just bottle 1, no 2

    • Janeth August 3, 2018 at 10:49 am Reply

      I CAme back here just to tell you if you decide to do this mms protocol , you may will throw up sometimes, please drink a lot of water other way you may gonna have a bit head ache, I think you will be ok if you have one a day cinnamon with honey, good luck😀

    • Janeth August 21, 2018 at 6:14 pm Reply

      Hi, I forgot to mention the you have to take 10ml of sea water 2 times or 3 times mix with water, I did 2 times a day

    • Janeth August 21, 2018 at 6:15 pm Reply

      Hi, I forgot to mention the you have to take 10ml of sea water 2 times or 3 times mix with water, I did 2 times a day🌹

    • Cameo Soul October 24, 2018 at 3:39 pm Reply

      Please be careful announcing ‘cure’ on here. Every one is different, some, like me, have underlying autoimmune disorders that limit our selection of natural supplements, and MANY may have an allergic reaction to the cinnamon. My father began having heart palps and sweats and difficulty breathing. There is no standard for sourcing of cinnamon and some are very dangerous in larger quantities like you find on vitamin shelf in capsule form.

      What works for one may not work for another. I have been suffering over 2.5 years after large intravenous dosing of Levoquin. Nerve damage is a permanent consequence and there is no ‘cure’ for damaged nerve pain of neuropathy. Only wise pain management.

      I have found pain is worse after eating and ran across a study saying the same neuro scensors that tell your body you are in pain are the same ones that tell you that you are hungry, and the hunger pangs will take precedence over the nerve pain.

      So most my day I manage by walking around hungry, and then take my OTC pain meds and Turmeric capsules about an hour before eating or I am in SEVERE pain for hours, sometimes whole night. I religiously take Move Free Ultra generic 2x a day and that has taken the edge off joint pain and tendon tightening. I used to feel like 100 year old when waking, unable to move, now I feel 70, lol, so not well, but much improved over immobile.

      Good luck and God Bless all with Floxing Syndrome.

    • James Ryan October 13, 2019 at 4:30 pm Reply

      WAIT! BE AWARE OF THE DANGER BEFORE TAKING MMS! Hi Janeth, Thank you for your long post and info, I’m glad MMS seemed to work for you BUT, here in the states studies are showing this water supplements are very dangerous. Most ‘floxies’ do not need more side effects- the FDA here is cracking down on the people selling these MMS agents because when mixed as packaging directs it basically becomes BLEACH. Please read this article here:
      before considering this. Looks like your post is from last year. i am curious if you continued taking this stuff and how it worked for you in the long run. Its just so hard to say what really works for each individual. i can’t even figure out what foods to make….someone tried Paleo diet-someone else said it was the worst thing….then we heard higher fiber but now roughage is out…this is absolutely insane..after 100 articles all i feel safe with is Magnesium, vitamin B (especially 12) and possibly fish oil…..for food i can only gather avocados, flax seeds and some fish. This is really rough when no doctor is helpful. I’m sitting here trying to make sense of the blood tests myself. The only thing that is certain is that red blood cell count is very low, so now I’m trying to find out if iron is OK- or will that cause another set back too. Good luck to you Janeth and everyone else. I know balancing the body is the answer its just finding the right intakes for that balance that makes it so hard!

  23. Rocky Marie October 5, 2018 at 1:45 pm Reply

    I’ve been Floxed in Late July 2018 and I’m still having symptoms. I’ve been taking vitamins for about a week now since I realized the symptoms were from the antibiotics., I’ve been really tired, weak and bones ache a lot any suggestions to help with this? Does anyone else have the same symptoms?

    • Brenda November 6, 2018 at 11:50 pm Reply

      I was floxed a year ago after 3 pills of Cipro. How are you doing? Have you noticed a difference in taking the vitamins. I still take a bunch of supplements. They have helped me. It took about 3 months to get through the worst of my symptoms. Brain fog, memory loss, depression, suicidal thoughts, anxiety, chest and abdominal pain, weakness on my left side, leg pulls and cramps, couldn’t hardly walk, terrible fatigue…I can’t remember all the side effects I have went through. Now they seem to come and go and everytime it’s different. I do feel better, not 100% yet. I take Magnesium Glysinate, CoQ10, B,D,E vitamins, Cucumin, Selenium, and a few others.

    • mp24hu February 23, 2019 at 7:43 pm Reply

      Please try fish oil + vitamin d. Also consider Ajwain tea in the seed. These things have worked for me.

  24. darko November 8, 2018 at 4:50 am Reply

    Hi Everyone, I took 56 Cipro pills over a period of 5 weeks. I was fine all the way until the end when I developed muscle cramps, pins and needles, twitches, etc etc. I am now trying to recover some 5 weeks later. I have recently developed pins and needles in my left let and numbness in my foot. Been ongoing for at least two weeks. Legs feel tired and heavy most of the time Also, I get numbness on top of my head (on/off) as if the skin in numb. Has anyone else experienced the same symptoms? Manythansk

    • mp24hu February 23, 2019 at 7:41 pm Reply

      I had the pins and needles in the legs and arms. I still do 8 months out but it did get better. It’s not as extreme.

  25. Lisa Davis January 22, 2019 at 10:52 pm Reply

    Hello everyone, I was recently in the hospital with diverticulitis abcess in colon. Treated in hospital with IV antibiotic penicillin based. After 6 days was sent home with 14 days worth of cipro and flagyl. Finished the round and was feeling better off the antibiotics. Had an appointment with the gastroenterologist in two more weeks. His office wanted me to continue the cipro and flagyl until my appointment. I resumed the medicine, started it back at night before bed. When I woke up next morning my right knee was swollen double and could hardly walk. Really scared me and I looked up the side effects and found the black box warning. Immediately stopped no more cipro and withing 24 hours the swelling in knee was reducing. 3 weeks later hands and thumbs started hurting me badly. Cannot do much with my hands and I’m assuming tendonitis. Also sore muscles, neck and shoulders. Even some chest or rib pains.
    I am scheduled for a colonoscopy in 2 weeks which will require a complete bowel clean out and anesthesia. Is it safe for me to do this right now? I just don’t know what to do. I am taking magnesium, Vit C but also need something for pain and advil not advised. Any suggestions appreciated.

    • Ernesto February 7, 2019 at 1:43 pm Reply

      Did you follow through with the anesthesia? I’m on the same boat. Thanks.

    • saskia April 23, 2019 at 12:20 am Reply

      magnesium is also a painrelieve. i got floxed in 18 march, from treatment for a urinary, took 7 days 2×500 mg a day cipro. i instantly had a heavy pain in my head, weakness in muscles, insomnia, loss of hungry, pains in bladder, a constantly buzz in my head, my right side of my face felt numb, my nose felt numb, when i touched slightly the skin of my legs it felt weird on the left leg , like it was a bit numb, constantly dizzy, pain in my eyes, later a constant shaking of hands, i am a painting artist and so doing the thing i love so much was difficult because of this and the dizzyness. But the first weeks i did not want to paint either, i was so depressed, sad, anxious and tired, i layed on my bed and couch, cried (what also was difficult, i was sad but my muscles were so tight i couldn’t cry) i kept telling myself okay you must get out and walk with the dog, because this isn’t good. so that wasthe only thing i managed to do. weak on legs, one time i got a migraine attack when walking with my neighbour, she was so nice for me, kept visiting and got me out of bed.

      I took magnesium and high vit c doses always as a treatment for my anxiety and stress that i always had. so when taking the cipro i stopped this but i took on the fifth day a high dosis of magnesium because my anxiety was so heavy. i immediately noticed my deppression and anxiety was less. but because the pain in my blatter was stille there and i did want the urinary infection to be gone i stopped with the magnesium again. but after quiting the cipro, i noticed some weird things and searched for sideeffects from this medicin. mostly because i found it weird that i couldn’t sleep properly. and i was so scared with what i read. i immediately began to treat myself with vitamins and minerals.

      *I took probiotics (also during the cipro), calcium+D3 and magnesium malate 1000mg, vitc 100mg (2x 500) but it didn’t do much.
      * for my neck and head muscles i went to my fysio, who has treated me very well for a accident a year before all this, and i couldn’t walk then because a sled had crashed into my calf. doctor in austria said it must be better in a week, but after three weeks i couldn’t stand on it nor walk and it hurted very bad) within 2 treatments i could get my feet on the floor and after a week i could get rid of my croutches. so i thought this is the men that can help me.
      So i went to him, i had the luck someone has called off so there was a spot free, because he is very very bussy. he treted me with dry needling and realy after a few treatments i felt my head pressure was less, not gone, but less. now my dizzyness is mostly gone, butsometimes it i get a dizzyattack for a few seconds and then its gone. my buzz is gone, the pressure is mostly gone, but i have some stiff muscles so im still being treated. What this men said was: “in over my years as a therapist i realy never ever had someone on my table with such stiff muscles in the neck. you could easily break a wouden chair on these muscles they’re like steel cables. I realy think this is because of the cipro.

      i take now :
      -probiotics (a real high one)
      – vit c 500mg in morning and one in the midday
      -600 ml of raspberry juice (high in vit E and antioxidants)
      -800 mg bisglycinate magnesium (very important for your brain)
      -2x 400 mg magnesium citrate (for the muscles)
      -1/2 tablet of solgar v multivitamin.

      much fruit: 1 apple, 7 mandarins, a pear, blueberries, strawberries

      in the morning 2 slices of bread with peanutbutter and choclat sprinkles and glas of water
      12:00 3 slices of bread with cheese, sprinkles and jam or honey
      18:00 potatoes with vegetables like broccoli or beans, spinach, flowercolly or something and meat.
      19:00 yoghurt with fresh blueberries or raspberries

      the one thing i like to know is how to get rid of the insommnia. i rely would like to sleep properly. now its like my brains is programmed to wake up every hour or hour and a half. it’s very frustrating because i want to sleep from 22:00 to 7:00 again.

  26. mp24hu February 23, 2019 at 7:38 pm Reply

    I’ve was floxed in July 2018 after 7 days of Cipro. Symptoms started with pain/needles in my legs and fingers. Once that went away it was bad headaches and extreme brain fog. I simply couldn’t think straight. I don’t know how I got through my work day. In late October things cleared…I felt back to myself. However after the new year my symptoms returned. I felt back at square one. I’m sitting here typing this with a smile on my face…because I may have turned the corner again and began the heal. Ive been taking a probiotic and magnesium. Recently I started fish oil with vitamin D. I’ve been starting to figure out what may be linked to a my turn around. Is it the fish oil ? Magnesium? Probiotics?
    One thing I didn’t mention is that I have been drinking Ajwain seed tea. Has anyone had experience with this? I know it can be very powerful. I was taking it during my “feel good months” but ran out and didn’t start taking it again until recently

  27. Michael June 12, 2020 at 1:26 pm Reply

    Is it possible to tolerate caffeine again someday? My body (about fifteen minutes after drinking it) starts to go a little haywire: stiffness, fatigue, etc. I’ve heard this does go away – but it takes years, is that true?

  28. Ashton August 8, 2020 at 11:41 am Reply

    What kind of Magnesium should you take and how much per day? I take a bone complex that has calcium in it, is calcium safe to take?

    Any supplement suggestions plus dosages would be greatly appreciated.


  29. Cary Bowers August 29, 2020 at 3:27 pm Reply

    I am recently floxed. No tendon issues but major neuropathy. I am terrified of permanent damage so I’m acting aggressively (so please respond ASAP) I am going to a doctor who will treat with IV vitamins (he says magenesium and glutathione is essential), stem cells, and ozone therapy. Has this helped anyone?

    • Faisal September 4, 2020 at 8:12 pm Reply

      Hi , Is our disease is fibromyalgia or what is our problem i cant find

      Sent from my iPhone


  30. SAM October 10, 2020 at 4:15 pm Reply

    REPORT-REPORT-REPORT to FDA using form 3500B :

    Affected 10/04/2020. Currently severe swelling in throat, neck, TMJ, eyes & mouth dry, have clicking, poping, tightness & spasms in back, major joints & major tendons. Tendon pain starting today. Head pain & headaches with light sensitivity & spots.

    I found warm to hot wet compresses help aleviate some issues & hard swelling (lump) & general swelling used over time better than ice does.

    I would consider holding epsom salt soaked facecloth on area but watch not get it in eye. It will take a while to reduce site (hard) swelling. My elbow joint (megadose floxied by IV in hospital 10/04, hard lump is at injection site) has hard swelling lump which lump has been reduced by half over 3 days with compress. I am on magnesium now. Took epsom salt bath thisorning. Hoping & praying to beat this quick. Thank you so all much for these posts! God Bless You All 🙂

  31. Linda January 11, 2021 at 2:16 pm Reply

    Can u recommend good magnesium and thiamine supplements to take and the dosage? Thank you.

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